CXCR4 Chemokine Receptor
| Structure Notes | PDB | Resolution [A] | Reference |
|---|---|---|---|
| complex with small molecule antagonist IT1t and cyclic peptide antagonist CVX15, T4 lysozyme insertion in 3rd intracellular loop, stabilizing mutations, crystallized in LCP (Cholesterol additive) | 3ODU, 3OE0, 3OE8, 3OE9, 3OE6 | 2.5 A, 2.9 A, 3.1 A, 3.1 A, 3.2 A | Wu, B. et al., Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists. Science 7 Oct 2010 |