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Fragment Screening | Drug discovery and development at Emerald BioStructures is enabled by a strong emphasis on structure-based drug design (SBDD) from both the target perspective by X-ray crystallography and the ligand perspective through tightly integrated computational chemistry and enzymology. Our assets in SBDD provide a clear understanding of structure activity relationships (SAR) for efficient ligand design. Our Fragments of Life™ (FOL™) technology represents a novel approach to fragment-based lead discovery and optimization. Fragments of Life™ is more than just a fragment library, it is a sound approach to identifying key starting point ligand architectures that have high ligand efficiency for binding to the target of interest. |
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