Crystal Ready™
Get insights from protein co-crystal structures with your ligands through our rapid and cost effective Crystal Ready™ program. Ligand-bound co-crystal structures provide valuable insights for medicinal chemistry programs and drug development studies. Our Crystal Ready™ offering includes more than 200 targets previously crystallized at Emerald BioStructures. All targets are available for rapid and affordable co-crystallization with your ligand(s) of interest, and also as ‘crystallographer grade’ purified protein. The Crystal Ready™ platform is loaded with highly relevant drug targets under investigation by talented drug hunters like you. Bring us your kinase inhibitor, protease inhibitor or other therapeutic candidate and we’ll help determine its molecular mechanism of action. Let Emerald reveal 3-dimensional binding information about your ligand that cannot come from anywhere else! Our expertise in structural biology coupled with our vast array of previously crystallized targets brings your ligand to life quickly and efficiently.
Request more information on rapid co-crystal structure determination.
The insights from three-dimensional ligand-bound structures can benefit any drug discovery or development program. Crystal Ready™ saves you time and money, which allows you to focus more resources on your true task, designing new molecules. Don’t see your target listed below? Ask us about our pipeline of target structures.
Kinase Targets
bRaf (V600E) NEW
Choline Kinase Alpha NEW
Cyclin dependent kinase 4 (mimic)
EGFR (Her kinase)
Hexokinase II NEW
Heme-regulated inhibitor kinase (HRI)
JNK3
KDR (VEGFR2)
cKit-wt
MAP2K2 (MEKK2)
MK2 (MEKK1)
cMet
P38α(- PO4)
P38α(+ PO4)
PDHK4 NEW
PI3Kgamma
Syk
Tankyrase 1 NEW
Tie2
ZAP-70 NEW
Other Targets
Alcohol dehydrogenase 1B NEW
APE1 NEW
Bcl-6 NEW
Carbonyl reductase 1 NEW
Caspase 2
Caspase 6
Cathepsin S
DcpS
Factor Xa
GSNOR NEW
Glutathione-S transferase 1 NEW
HCV Polymerase (NS5b)
HCV Protease (NS3/4a)
HCV NS5a Domain I
HDAC4
HRas-wt NEW
HRas- G12D NEW
HSP90
IDH1 (R132H) NEW
Kallikrein-1
LpxC
NAMPT NEW
PDE1B NEW
PDE4B (Cat.)
PDE4D (Cat.)
PHD2
PHGDH NEW
PPARgamma
Phosphoserine Aminotransferase 1 NEW
Phosphoserine Phosphatase NEW
PTP1B
Recombinase A NEW
RNAaseL NEW
Serine Dehydratase NEW
SPLY1
Thrombin
Infectious Disease Targets
3-oxoacyl-(acyl carrier protein) synthase II, 3E60
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase , 3MBM
2-dehydro-3-deoxyphosphooctonate aldolase , 3FS2
3-ketoacyl-(acyl-carrier-protein), 3LLS
3-ketoacyl-(acyl-carrier-protein) reductase, 3F9I
3-methyl-2-oxobutanoate hydroxymethyltransferase, 3EZ4
3-oxoacyl-(acyl carrier protein) synthase II, 3KZU
3-oxoacyl-(acyl-carrier-protein) synthase III, 3GWA
6-phosphogluconolactonase, 3ICO
7-alpha-hydroxysteroid dehydrogenase, 3GAF
acetoacetyl-CoA reductase, 3GK3
acetylpolyamine aminohydrolase, 3MEN
acyl carrier protein, 2KWL
acyl-carrier-protein S-malonyltransferase, 3EZO
adenylate kinase, 3GMT
alanine racemase , 3KW3
alcohol dehydrogenase, 3MEQ
Aldehyde dehydrogenase, 3EK1
aldose reductase, 3KRB
Amino acid-binding ACT:D-isomer specific 2-hydroxyacid dehydrogenase, 3K5P
arginine/ornithine transport system ATPase, 3MD0
arsenate reductase (ArsC) related protein, 2KOK
Bacterioferritin, 3FVB
Beta-ketoacyl synthase, 3LRF
beta-lactamase-like protein, 3MD7
cytidine deaminase, 3DMO
cytoplasmic aspartate aminotransferase, 3MEB
deoxyribose phosphate aldolase, 3NDO
deoxyuridine 5-triphosphate nucleotidohydrolase, 3LQW
dihydrodipicolinate reductase, 3IJP
Dihydrofolate reductase/thymidylate synthase, 3I3R
DNA PolC, 3F2B
enoyl-(acyl carrier protein) reductase, 3EK2
enoyl-CoA hydratase, 3H81
Eoxycytidine triphosphate deaminase, 3KM3
Extragenic suppressor protein suhB, 3LUZ
Ferritin:DNA-binding protein Dps, 3GE4
fructose bisphosphate aldolase, 3MBD
fructose-1,6-bisphosphate aldolase, 3KX6
fumarate hydratase, 3GTD
glucosamine-6-phosphate deaminase, 3HN6
Glucose/ribitol dehydrogenase, 3EMK
Glutaredoxin, 2KLX
glutaryl-CoA dehydrogenase, 3D6B
glyceraldehyde 3-phosphate dehydrogenase (gap), 3HJA
glycine cleavage system protein H, 3HGB
Glycine cleavage system protein t, 3GIR
Guanylate Kinase, 3LNC
HAD-superfamily hydrolase, subfamily IA, variant 1, 3KZX
HCV NS3 (Helicase), 3KQH
HCV NS3/4a (Protease), 2XCF
HCV NS5b (Polymerase), 3HKW
Hep_Hag family / Haemagluttinin family protein xadA, 3LAA
hexapeptide transferase family protein, 3IXC
Hit-like protein involved in cell-cycle regulation, 3LB5
hydrolase TatD family protein, 3IPW
inorganic pyrophosphatase, 3D53
Iron superoxide dismutase , 3JS4
Isocitrate dehydrogenase, 3DMS
isocitrate lyase, 3E5B
isoprenoid biosynthesis protein with amidotransferase-like domain, 3L3B
Kinase, CMGC CDK, 3GBZ
Large c-terminal domain of PB2, 3KC6
LpxC, 2VES
macrophage binding protein, 3N7T
malate dehydrogenase, 3D5T
malonyl CoA-acyl carrier protein transacylase, 3G87
methionine aminopeptidase, 3MR1
methionine aminopeptidase, 3MX6
methionine-R-sulfoxide reductase, 3CEZ
methionine-R-sulfoxide reductase, 3CXK
methylcitrate synthase, 3HWK
methylisocitrate lyase, 3EOO
MetRS, 3H9C
mutator mutt, 3HHJ
NAD+ synthase, 3DPI
N-ethylmaleimide reductase, 3GKA
nicotinate-nucleotide pyrophosphorylase, 3GNN
Nucleoside diphosphate kinase family protein, 3JS9
O-siccinylhomoserine sulfhydrylase, 3NDN
Pantoate-beta-alanine ligase:Cytidyltransferase-related domain, 3INN
peptidyl-prolyl cis-trans isomerase, 2KE0
Periplasmic domain of the risS sensor protein, low pH native structure, 3LR3
PFE0790c hypothetical protein, conserved, 2KDN
phosphoglycerate mutase, 3EZN
Phosphoglyceromutase, 3LNT
phosphopantetheine adenylyltransferase, 3IKZ
phosphoribosylamine-glycine ligase, 3LP8
phosphoribosylaminoimidazole-succinocarboxamide synthase, 3KRE
phosphoribosylglycinamide formyltransferase, 3KCQ
Plasmid partition protein, 3K9G
Possible Dehydrogenase, 3KHP
Precorrin-8X methylmutase CbiC/CobH, 3E7D
probable enoyl-CoA hydratase, 3MOY
probable short-chain type dehydrogenase/reductase, 3GVC
PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2, 3HWI
PROBABLE THIOSULFATE SULFURTRANSFERASE SSEA, 3HZU
Protein Rv0543c, 2KVC
protein tyrosine phosphatase, 3ILY
Putative conserved protein mbtH,2KHR
putative diphthine synthase,3I4T
Putative endoribonuclease L-PSP, 3M1X
putative glutathione transferase, 3LG6
pyridoxal phosphate biosynthetic protein, 3GK0
RecA, 1XMV
ribose-5-phosphate isomerase, 3HHE
ribose-phosphate pyrophosphokinase, 3DAH
RNA methyltransferase, TrmH, 3E5Y
Rubredoxin, 2KN9
S adenosyl-L-homocysteine hydrolase, 3N58
SAM synthase, 3IML
serine hydroxymethyltransferase, 3ECD
Short-chain dehydrogenase/reductase SDR:Glucose/ribitol dehydrogenase, 3GRK
single-stranded binding protein, 3LGJ
succinate-semialdehyde dehydrogenase (NADP+), 3IFG
tetrahydropyridine 2-carboxylate N-succinyl transferase, 3EG4
Thymidylate Kinase, 3LD9
Thymidylate synthase (EC 2.1.1.45) thyA, 3IX6
Thymidylate synthase 1/2 TS-1, 3KGB
Thymidylate Synthase X, 3GWC
transcriptional cofactor/pterin hydratase, 3JST
triosephosphate isomerase , 3GVG
TrkA glyceraldehyde-3-phosphate dehydrogenase, 3DOC
tRNA (guanine-n1)-methyltransferase, 3IEF
UDP-glucose 4 epimerase, 3ENK
uracil phosphoribosyltransferase, 3DMP