Fast, inexpensive ligand-bound co-crystal structure
Emerald can crystallize any soluble (non-membrane protein) single chain target that has been reported in the Protein Data Bank (PDB). If more than one structure is reported, or if the structure came from an international protein structure initiative, Emerald can reproduce it with your ligand quickly and cost effectively.
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Aurora-A, 2X81
Aurora-B, 2VGO
Caspase-1, 2HBQ
Caspase-3, 3H0E
Cathepsin B, 3K9M
Cathepsin K, 3H7D
Cathepsin L1, 3HWN
Chymase, 1NN6
DPP IV, 3G0B
EGFR, 3GT8
Elastase-2, 2RG3
EphA2, 3FL7
EPHB4, 2VWX
ERK2 (MAPK2), 3I5Z
FAK1, 3BZE
HCK, 2C0I
JNK1, 3ELJ
JNK2, 3E7O
LXR alpha, 3IPQ
LXR beta, 1UPW
MARK1, 2HAK
MARK2, 2WZJ
MARK3, 3FE3
MCL-1, 3KJ0
MMP-13, 3I7G
MMP-9, 2OVX
Nek2, 2WQO
PAK1, 3FY0
PAK4, 2Q0N
PDE2A, 3IBJ
PDE5A, 3HC8
PDE7A, 3G3N
PDE10A, 3LXG
PIM1, 3MA3
PIN1, 3I6C
PKC iota, 3A8W
PKC tau, 1SZM
PLK1, 3KB7
PLK4, 3COK
ROCK1, 3D9